affliction, aggravation, ambulatory plague, annoyance, annoyer, bad news, badgerer, bane, bedevilment, besetment, black death, black plague, blast, blight, bore, bother, botheration, bothersomeness, bubonic plague, bugbear, bully, burden, buttonholer, calamity, cancer, canker, cellulocutaneous plague, crashing bore, crushing burden, curse, death, defervescing plague, destruction, devilment, difficulty, disease, dogging, downer, drag, drip, dry rot, dryasdust, dusty, epidemic, epiphytotic, epizootic, evil, exasperation, flat tire, frightful bore, fungus, gadfly, glandular plague, grievance, harasser, harassment, harm, harrier, harrying, headache, heckler, hemorrhagic plague, hounding, humdrum, infliction, irritant, larval plague, mildew, mold, molestation, moth, moth and rust, murrain, must, nag, nemesis, nudnik, nudzh, nuisance, open wound, pandemia, pandemic, persecution, persecutor, pester, pesterer, pesthole, pestilence, pill, plague, plague spot, plaguer, pneumonic plague, premonitory plague, problem, proser, rot, running sore, rust, sadist, scourge, septicemic plague, siderating plague, smut, tease, teaser, thorn, torment, tormentor, trial, trouble, tuberculosis, twaddler, vexation, vexatiousness, visitation, wet blanket, white plague, woe, worm, worriment, worry
bane, curse, evil, hurtfulness, painfulness, scourge, damnosa hereditas, white elephant, sting, fang, thorn, tang, bramble, brier, nettle, poison, toxin, teratogen, leaven, virus venom, arsenic, antimony, tartar emetic, strychnine, nicotine, miasma, miasm, mephitis, malaria, azote, sewer gas, pest
, Albany hemp, arsenious oxide, arsenious acid, bichloride of mercury, carbonic acid, carbonic gas, choke damp, corrosive sublimate, fire damp, hydrocyanic acid, cyanide, Prussic acid, hydrogen cyanide, marsh gas, nux vomica, ratsbane, hemlock, hellebore, nightshade, belladonna, henbane, aconite, banewort, bhang, ganja, hashish, Upas tree, Toxline (online), rust, worm, helminth, moth, moth and rust, fungus, mildew, dry rot, canker, cankerworm, cancer, torpedo, viper, demon, toxicology, baneful, poisonous, phr, bibere venenum in auro, Contingent Subservience.
painfulness, trouble, care, trial, affliction, infliction, blow, stroke, burden, load, curse, bitter pill, bitter draught, waters of bitterness, annoyance, grievance, nuisance, vexation, mortification, sickener, bore, bother, pother, hot water, sea of troubles, hornet's nest, plague, pest
, cancer, ulcer, sting, thorn, canker, scorpion, dagger, scourge, carking care, canker worm of care, mishap, misfortune, desagrement, esclandre, rub, source of irritation, source of annoyance, wound, open sore, sore subject, skeleton in the closet, thorn in the flesh, thorn in one's side, where the shoe pinches, gall and wormwood, sorry sight, heavy news, provocation, affront, head and front of one's offending, infestation, molestation, malignity, causing pain, hurting, hurtful, painful, dolorific, dolorous, unpleasant, unpleasing, displeasing, disagreeable, unpalatable, bitter, distasteful, uninviting, unwelcome, undesirable, undesired, obnoxious, unacceptable, unpopular, thankless, unsatisfactory, untoward, unlucky, uncomfortable, distressing, afflicting, afflictive, joyless, cheerless, comfortless, dismal, disheartening, depressing, depressive, dreary, melancholy, grievous, piteous, woeful, rueful, mournful, deplorable, pitiable, lamentable, sad, affecting, touching, pathetic, irritating, provoking, stinging, annoying, aggravating, mortifying, galling, unaccommodating, invidious, vexatious, troublesome, tiresome, irksome, wearisome, plaguing, plaguy, awkward, importunate, teasing, pestering, bothering, harassing, worrying, tormenting, carking, intolerable, insufferable, insupportable, unbearable, unendurable, past bearing, not to be borne, not to be endured, more than flesh and blood can bear, enough to drive one mad, enough to provoke a saint, enough to make a parson swear, enough to gag a maggot, shocking, terrific, grim, appalling, crushing, dreadful, fearful, frightful, thrilling, tremendous, dire, heart-breaking, heart-rending, heart-wounding, heart-corroding, heart-sickening, harrowing, rending, odious, hateful, execrable, repulsive, repellent, abhorrent, horrid, horrible, horrific, horrifying, offensive, nauseous, nauseating, disgusting, sickening, revolting, nasty, loathsome, loathful, fulsome, vile, hideous, sharp, acute, sore, severe, grave, hard, harsh, cruel, biting, caustic, cutting, corroding, consuming, racking, excruciating, searching, grinding, grating, agonizing, envenomed, catheretic, pyrotic, ruinous, disastrous, calamitous, tragical, desolating, withering, burdensome, onerous, oppressive, cumbrous, cumbersome, painfully, with pain, deuced, Int, hinc illae lachrymae!, surgit amari aliquid, the place being too hot to hold one, the iron entering into the soul, he jests at scars that never felt a wound, I must be cruel only to be kind, what deep wounds ever closed without a scar?.
animal, animal kingdom, fauna, brute creation, beast, brute, creature, critter, wight, created being, creeping thing, living thing, dumb animal, dumb creature, zoophyte, mammal, bird, reptile, amphibian, fish, crustacean, shellfish, mollusk, worm, insect, arthropod, microbe, microbe, animalcule, alligator, crocodile, saurian, dinosaur (extinct), snake, serpent, viper, eft, asp, aspick, frog, toad, trout, bass, tuna, muskelunge, sailfish, sardine, mackerel, ant, mosquito, bee, honeybee, tardigrade, spider, biped, quadruped, webfoot, flocks and herds, live stock, domestic animals, wild animals, game, ferae naturae, beasts of the field, fowls of the air, denizens of the sea, black game, black grouse, blackcock, duck, grouse, plover, rail, snipe, horse, cattle, kine, ox, bull, bullock, cow, milch cow, calf, heifer, shorthorn, sheep, lamb, lambkin, ewe, ram, tup, pig, swine, boar, hog, sow, steer, stot, tag, teg, bison, buffalo, yak, zebu, dog, cat, dog, hound, pup, puppy, whelp, cur, mongrel, house dog, watch dog, sheep dog, shepherd's dog, sporting dog, fancy dog, lap dog, toy dog, bull dog, badger dog, mastiff, blood hound, grey hound, stag hound, deer hound, fox hound, otter hound, harrier, beagle, spaniel, pointer, setter, retriever, Newfoundland, water dog, water spaniel, pug, poodle, turnspit, terrier, fox terrier, Skye terrier, Dandie Dinmont, collie, feline, puss, pussy, grimalkin, gib cat, tom cat, fox, Reynard, vixen, stag, deer, hart, buck, doe, roe, caribou, coyote, elk, moose, musk ox, sambar, bird, poultry, fowl, cock, hen, chicken, chanticleer, partlet, rooster, dunghill cock, barn door fowl, feathered tribes, feathered songster, singing bird, dicky bird, canary, warbler, finch, aberdevine, cushat, cygnet, ringdove, siskin, swan, wood pigeon, vermin, varmint, pest
, animal, zoological equine, bovine, vaccine, canine, feline, fishy, piscatory, piscatorial, molluscous, vermicular, gallinaceous, rasorial, solidungulate, soliped.