Verb has 1 sense

• fuck up(v = verb.social) ball up, blow, bobble, bodge, bollix, bollix up, bollocks, bollocks up, botch, botch up, bumble, bungle, flub, fluff, foul up, fumble, louse up, mess up, mishandle, muck up, muff, screw up, spoil - make a mess of, destroy or ruin; "I botched the dinner and we had to eat out"; "the pianist screwed up the difficult passage in the second movement"

Derived form noun fuckup₂
Sample sentences:
Somebody ----s
Somebody ----s something