ablate, abrade, abrase, abrasion, acerbity, acid, acidity, acidulousness, acridity, acridness, acrimony, afflict, affliction, aggravate, aggravation, agonize, ail, anger, animosity, annoy, annoyance, arouse, arrogance, asperity, astringence, astringency, audacity, autacoid, bad humor, bad temper, badger, balls, bark, bedevil, bile, bilge, biliousness, bite, bitter cup, bitter draft, bitter draught, bitter pill, bitter resentment, bitterness, bitterness of spirit, blain, bleb, blemish, blister, blob, bloody, boss, bother, bow, brashness, brass, brazen boldness, brazenness, break, bubble, bulb, bulge, bulla, bump, bunch, burden, burden of care, burl, burn, burn up, button, cahot, cankerworm of care, care, causticity, causticness, chafe, chalone, check, cheek, chide, chine, chip, choler, chutzpah, claw, clump, conceit, concussion, condyle, confidence, convex, convulse, corrosiveness, crack, crackle, craze, cross, crown of thorns, crucify, crust, curse, cut, digestive secretion, discontent, distress, disturb, dowel, ear, effrontery, embitterment, encumbrance, endocrine, enrage, erase, erode, exacerbate, exacerbation, exasperate, exasperation, excoriate, excruciate, exercise, face, fester, file, flange, flap, flash burn, fracture, fray, frazzle, fret, front, gall and wormwood, gash, gastric juice, get, give pain, gnarl, gnashing of teeth, gnaw, gnaw away, goad, grate, grate on, gravel, graze, grievance, grind, gripe, grit, guts, handle, harass, hard feelings, harrow, harry, harshness, haughtiness, heartburning, hector, heroics, hill, hormone, hubris, hump, hunch, hurt, ill humor, ill nature, ill temper, impertinence, improvidence, imprudence, impudence, incense, incise, incision, indiscretion, inflame, inflict pain, infliction, infuriate, injudiciousness, injure, injury, insolence, intestinal juice, irk, irritant, irritate, irritation, jog, joggle, kill by inches, knob, knot, knur, knurl, lacerate, laceration, lesion, lip, load, loftiness, loop, lordliness, lump, maim, make mincemeat of, martyr, martyrize, maul, mole, mordacity, mortal wound, mountain, moxie, mucus, mutilate, mutilation, nag, needle, nerve, nettle, nevus, nip, nub, nubbin, nubble, nuisance, oppression, overbearance, overboldness, overcarelessness, overconfidence, oversureness, overweeningness, pack of troubles, pain, pancreatic juice, papilloma, peck of troubles, peg, pester, pierce, pinch, plague, poison, pomposity, presumption, prick, pride, priggishness, prolong the agony, prostatic fluid, provocation, provoke, puncture, pungency, put to torture, rack, rancidity, rancidness, rancor, rankle, rankling, rashness, rasp, raze, rend, rent, rheum, rib, ridge, rile, ring, rip, roil, rub, rub away, rub off, rub out, ruffle, run, rupture, salivary secretion, sauce, sauciness, savage, scald, scorch, score, scotch, scour, scrape, scratch, scrub, scuff, sea of troubles, second-degree burn, self-importance, semen, set on edge, sharpness, shoulder, skin, slash, slit, slow burn, smugness, sore, sore spot, soreness, sorrow, sourness, sperm, spine, spleen, sprain, stab, stab wound, stick, sting, strain, stud, style, tab, tartness, tear, tears, temerariousness, temerity, third-degree burn, thorn, thyroxin, torment, torture, trauma, traumatize, trouble, tubercle, tubercule, tweak, twist, unchariness, unwariness, venom, venomousness, verruca, vesicle, vex, vexation, virulence, vitriol, wale, wart, waters of bitterness, wear, wear away, weight, welt, woe, worry, wound, wounds immedicable, wrench, wring
cause pain, occasion pain, give pain, bring pain, induce pain, produce pain, create pain, inflict pain, pain, hurt, wound, pinch, prick, gripe, pierce, lancinate, cut, hurt the feelings, wound the feelings, grate upon the feelings, grate upon the nerves, jar upon the feelings, wring the heart, pierce the heart, lacerate the heart, break the heart, rend the heart, make the heart bleed, tear the heart strings, rend the heart strings, draw tears from the eyes, sadden, make unhappy, plunge into sorrow, grieve, fash, afflict, distress, cut up, cut to the heart, displease, annoy, incommode, discompose, trouble, disquiet, faze, feaze, feeze, disturb, cross, perplex, molest, tease, tire, irk, vex, mortify, wherret, worry, plague, bother, pester, bore, pother, harass, harry, badger, heckle, bait, beset, infest, persecute, importune, wring, harrow, torment, torture, bullyrag, put to the rack, put to the question, break on the wheel, rack, scarify, cruciate, crucify, convulse, agonize, barb the dart, plant a dagger in the breast, plant a thorn in one's side, irritate, provoke, sting, nettle, try the patience, pique, fret, rile, tweak the nose, chafe, gall, sting to the quick, wound to the quick, cut to the quick, aggrieve, affront, enchafe, enrage, ruffle, sour the temper, give offense, maltreat, bite, snap at, assail, smite, sicken, disgust, revolt, nauseate, disenchant, repel, offend, shock, stink in the nostrils, go against the stomach, turn the stomach, make one sick, set the teeth on edge, go against the grain, grate on the ear, stick in one's throat, stick in one's gizzard, rankle, gnaw, corrode, horrify, appal, appall, freeze the blood, make the flesh creep, make the hair stand on end, make the blood curdle, make the blood run cold, make one shudder, haunt the memory, weigh on the heart, prey on the heart, weigh on the mind, prey on the mind, weigh on the spirits, prey on the spirits, bring one's gray hairs with sorrow to the grave, add a nail to one's coffin.
resentment, displeasure, animosity, anger, wrath, indignation, exasperation, bitter resentment, wrathful indignation, pique, umbrage, huff, miff, soreness, dudgeon, acerbity, virulence, bitterness, acrimony, asperity, spleen, gall, heart-burning, heart-swelling, rankling, ill humor, bad humor, ill temper, bad temper, irascibility, ill blood, revenge, excitement, irritation, warmth, bile, choler, ire, fume, pucker, dander, ferment, ebullition, towering passion, acharnement, angry mood, taking, pet, tiff, passion, fit, tantrums, burst, explosion, paroxysm, storm, rage, fury, desperation, violence, fire and fury, vials of wrath, gnashing of teeth, hot blood, high words, scowl, sulks, affront, provocation, offense, indignity, grudge, crow to pluck, bone to pick, sore subject, casus belli, ill turn, outrage, Furies, Eumenides, buffet, slap in the face, box on the ear, rap on the knuckles, angry, wrath, irate, ireful, wrathful, cross, Achillean, sulky, bitter, virulent, acrimonious &c (discourteous), violent, warm, burning, boiling, boiling over, fuming, raging, foaming, foaming at the mouth, convulsed with rage, offended, waxy, acharne, wrought, worked up, indignant, hurt, sore, set against, fierce, wild, rageful, furious, mad with rage, fiery, infuriate, rabid, savage, relentless, flushed with anger, flushed with rage, in a huff, in a stew, in a fume, in a pucker, in a passion, in a rage, in a fury, in a taking, in a way, on one's high ropes, up in arms, in high dudgeon, angrily, in the height of passion, in the heat of passion, in the heat of the moment, Int, tantaene animis coelestibus irae!, marry come up!, zounds!, 'sdeath!, one's blood being up, one's back being up, one's monkey being up, fervens difficili bile jecur, the gorge rising, eyes flashing fire, the blood rising, the blood boiling, haeret lateri lethalis arundo, beware the fury of a patient man, furor arma ministrat, ira furor brevis est, quem Jupiter vult perdere dementat prius, What, drunk with choler?.
malevolence, bad intent, bad intention, unkindness, diskindness, ill nature, ill will, ill blood, bad blood, enmity, hate, malignity, malice, malice prepense, maliciousness, spite, despite, resentment, uncharitableness, incompassionateness, gall, venom, rancor, rankling, virulence, mordacity, acerbity churlishness, hardness of heart, heart of stone, obduracy, cruelty, cruelness, brutality, savagery, ferity, ferocity, barbarity, inhumanity, immanity, truculence, ruffianism, evil eye, cloven foot, torture, vivisection, ill turn, bad turn, affront, outrage, atrocity, ill usage, intolerance, persecution, tender mercies, unkindest cut of all, malevolent, unbenevolent, unbenign, ill-disposed, ill-intentioned, ill-natured, ill-conditioned, ill-contrived, evil-minded, evil- disposed, black-browed, malicious, malign, malignant, rancorous, despiteful, spiteful, mordacious, caustic, bitter, envenomed, acrimonious, virulent, unamiable, uncharitable, maleficent, venomous, grinding, galling, harsh, disobliging, unkind, unfriendly, ungracious, inofficious, invidious, uncandid, churlish, surly, sullen, cold, cold-blooded, cold-hearted, black-hearted, hard-hearted, flint-hearted, marble-hearted, stony-hearted, hard of heart, unnatural, ruthless, relentless, cruel, brutal, brutish, savage, savage as a bear, savage as a tiger, ferine, ferocious, inhuman, barbarous, barbaric, semibarbaric, fell, untamed, tameless, truculent, incendiary, bloodthirsty, atrocious, bloodyminded, fiendish, fiendlike, demoniacal, diabolic, diabolical, devilish, infernal, hellish, Satanic, Tartaran, malevolently, with bad intent, cruel as death, hard unkindness' alter'd eye, homo homini lupus, mala mens, malus animus, rich gifts wax poor when givers prove unkind, sharp-tooth'd unkindness.
feel pain, experience pain, suffer pain, undergo pain, suffer, ache, smart, bleed, tingle, shoot, twinge, twitch, lancinate, writhe, wince, make a wry face, sit on thorns, sit on pins and needles, give pain, inflict pain, lacerate, pain, hurt, chafe, sting, bite, gnaw, gripe, pinch, tweak, grate, gall, fret, prick, pierce, wring, convulse, torment, torture, rack, agonize, crucify, cruciate, excruciate, break on the wheel, put to the rack, flog, grate on the ear.
bitterness, acridness, acridity, acrimony, caustic, alkali, acerbity, gall, wormwood, bitters, astringent bitters, Angostura, aromatic bitters, sourness, pungency, alkaloids, turmeric, bitter, bitterish, acrid, acerb, acerbic, bitter as gall, bitter pill to take, sugar coating on a bitter pill.