loco disease(n = noun.state) locoism - a disease of livestock caused by locoweed poisoning; characterized by weakness and lack of coordination and trembling and partial paralysis;
A chronic nervous affection of cattle, horses, and sheep, caused by eating the loco weed and characterized by a slow, measured gait, high step, glassy eyes with defective vision, delirium, and gradual emaciation. [Webster 1913 Suppl.]