THESAURUS
despond
abandon hope, become suicidal, brood, despair, despair of, droop, falter, give up, give up hope, give way, hit rock bottom, languish, lose heart, lose hope, plumb the depths, reach the depths, sag, sink, sink into despair, touch bottom, yield to despair
ROGET THESAURUS
despond
Dejection
VB
be dejected, grieve, mourn, take on, give way, lose heart,
despond, droop, sink, lower, look downcast, frown, pout, hang down the head, pull a long face, make a long face, laugh on the wrong side of the mouth, grin a ghastly smile, look blue, look like a drowned man, lay to heart, take to heart, mope, brood over, fret, sulk, pine, pine away, yearn, repine, despair, refrain from laughter, keep one's countenance, be grave, look grave, repress a smile, depress, discourage, dishearten, dispirit, damp, dull, deject, lower, sink, dash, knock down, unman, prostrate, break one's heart, frown upon, cast a gloom, cast a shade on, sadden, damp one's hopes, dash one's hopes, wither one's hopes, weigh on the mind, lie heavy on the mind, prey on the mind, weigh on the spirits, lie heavy on the spirits, prey on the spirits, damp the spirits, depress the spirits.
Hopelessness
VB
despair, lose all hope, give up all hope, abandon all hope, relinquish all hope, lose the hope of, give up the hope of, abandon the hope of, relinquish the hope of, give up, give over, yield to despair, falter,
despond, jeter le manche apres la cognee, inspire despair, drive to despair, disconcert, dash one's hopes, crush one's hopes, destroy one's hopes, hope against hope, abandon, resign, surrender, submit.