cfc(n = noun.substance) chlorofluorocarbon - a fluorocarbon with chlorine; formerly used as a refrigerant and as a propellant in aerosol cans; "the chlorine in CFCs causes depletion of atmospheric ozone"
cfc, abbr. Chem. chloro-fluorocarbon, any of various usu. gaseous compounds of carbon, hydrogen, chlorine, and fluorine, used in refrigerants, aerosol propellants, etc., and thought to be harmful to the ozone layer in the earth's atmosphere.