a severe form of physiological shock, often having a fatal outcome, caused by an extreme immunological reaction to antigens. It is a severe form of
anaphylaxis{2}, and is characterized by smooth muscle contraction and capillary dilation throughout the body, initiated by antibodies of the IgE class. It is usually seen when an antigen to which a person has become hypersensitized is injected intravenously or subcutaneously. It is also called
generalyzed anaphylaxis or
systemic anaphylaxis, and sometimes
anaphylaxis. [
PJC]