The root of a plant (Jateorrhiza Calumba, and probably Cocculus palmatus), indigenous in Mozambique. It has an unpleasantly bitter taste, and is used as a tonic and antiseptic. [1913 Webster]
American calumba, the Frasera Carolinensis, also called American gentian. Its root has been used in medicine as bitter tonic in place of calumba.